0001816736 2026-11-05 2026-11-05 0001816736 1 2026-11-05 2026-11-05 0001816736 1 2026-11-05 2026-11-05 0001816736 2 2026-11-05 2026-11-05 iso4217:USD pure S-3 424B5 EX-FILING FEES 333-281359 0001816736 Disc Medicine, Inc. N/A true false S-3 Disc Medicine, Inc. false Equity Common Stock, par value $0.0001 per share true 189925765.00 0.000087 16523.54 189925765.00 16523.54 0.00 16523.54 0.00 The registration fee is calculated in accordance with Rule 457(o) under the Securities Act of 1933, as amended (the "Securities Act"), based on the proposed maximum aggregate offering price, and Rule 457(r) under the Securities Act. In accordance with Rules 456(b) and 457(r) under the Securities Act, the registrant initially deferred payment of all of the registration fee for its Registration Statement on Form S-3ASR (Registration No. 333-281359), which was filed with the Securities and Exchange Commission on August 8, 2024. Pursuant to Rule 457(p) under the Securities Act, the registrant hereby applies $16,523.54 of the registration fee previously paid in connection with the Prior Prospectus Supplement (as defined below) to offset the registration fees that are payable in connection with the registration of securities on this prospectus supplement. true Disc Medicine, Inc. S-3 333-281359 2024-08-08 16523.54 Equity Common Stock, par value $0.0001 per share 189925765.25 true Disc Medicine, Inc. S-3 333-275652 2023-11-20 59040.00 On August 8, 2024, the registrant filed a registration statement on Form S-3ASR (File No. 333-281359) and on November 15, 2024, the registrant filed a sales agreement prospectus supplement covering the offering, issuance and sale by the registrant of up to an aggregate of $200,000,000 of its common stock pursuant to its "at-the-market" offering program with Cantor Fitzgerald & Co. (the "Prior Prospectus Supplement"). The registrant incurred a filing fee in the amount of $30,620 in connection with the Prior Prospectus Supplement, which fee was calculated pursuant to Rule 457(o) under the Securities Act. Of this amount, $25,144.84 was offset pursuant to Rule 457(p) under the Securities Act by previously paid registration fees attributable to unsold securities under the registrant's prior "at-the-market" offering with Jefferies LLC, registered pursuant to the registrant's registration statement on Form S-3 filed on November 20, 2023 (File No. 333-275652) (the "Source Registration Statement"). The registrant previously paid an aggregate registration fee of $59,040 in connection with the Source Registration Statement (based on the filing fee rate in effect at the time of the filing of the Source Registration Statement). As of the date of filing of this prospectus supplement, $189,925,765.25 of shares of the registrant's common stock (the "Unsold Securities") remained unsold under the Prior Prospectus Supplement, representing $29,077.63 in registration fees attributable to such Unsold Securities under the Prior Prospectus Supplement. Pursuant to Rule 457(p) under the Securities Act, filing fees in the amount of $16,523.54 relating to a portion of the Unsold Securities are being carried forward, and the offering pursuant to the Prior Prospectus Supplement is deemed terminated. 189925765.00 true